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KMID : 0603820080140030173
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Journal of Experimental & Biomedical Science
2008 Volume.14 No. 3 p.173 ~ p.178
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Effects of Various Laser Wavelengths and Power Densities on the Ocular Damage in Pigmented Rats
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Chung Phil-Sang
Ahn Jin-Chul
Chang Moo-Hwan
Hwang Hee-Jun
Chang So-Young
Kang Jung-Wook
Shin Jang-In
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Abstract
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With the widespread use of laser in medical and industrial settings, the incidence of laser injury to the ocular continues to grow among workers involved in handling lasers. The aim of this study is to compare ocular damages after irradiation with various laser wavelengths and power density. Ocular of pigmented rats was irradiated with CO₂ laser, 1064 ㎚ Nd:YAG laser, and 532 ㎚ diode laser. We observed damage of cornea, lens, and retina using slit lamp microscope and funduscopy. H&E staining of histopathology were applied to study the specimens. The higher exposure (200 ㎽/㎠, 10 sec) with CO₂ laser resulted in severe damage at the cornea. For the 1064 ㎚ Nd:YAG laser, the higher exposure than 10 ㎽/㎠ (10 sec) resulted in damage at the cornea and lens. Further, with the 532 ㎚ diode laser, retinal lesions were induced when 10 ㎽/㎠ (0.25 sec) was delivered to the eye. Theses results suggest that the ocular damages are different from various laser wavelength and power density.
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KEYWORD
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CO₂ laser, Nd:YAG laser, Diode laser, Ocular damage, MPE(Maximal permissible exposure)
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